Yes, but my question is different I think:

ej:

odoo in port 8069 and longpolling 8072

odoo2 in port 8070 and longpolling 8072

Any problem with that configuration?

Nope, It will not

For odoo -->> 2017-04-27 11:00:51,492 11829 INFO ? openerp.service.server: Evented Service (longpolling) running on 0.0.0.0:8072

For Odoo2 -->> socket.error: [Errno 98] Address already in use: ('0.0.0.0', 8072)

Great, ports longpolling diferents in same machine.

Thanks