In Odoo Helpdesk, there is a setting to exclude cc'd recipients from generating tickets. Here's how you can configure it:

Go to the Helpdesk app and open the Settings menu.
Click on the Email tab.
Under the Email Alias section, select the email alias for which you want to exclude cc'd recipients from generating tickets.
Scroll down to the "Advanced Settings" section and set the "Create Ticket from CC" option to "No".
Save the changes.

With this setting, when an email is received at the selected email alias, only the main recipients will generate tickets, and the cc'd recipients will be excluded.