Nope, not by default. In an absolutely horrible to work with reporting system, Odoo left this major report out. You have to create multiple data sets from multiple modules, merge them, de-duplicate them, and you still won't have a 100% accurate sales report that includes all sales channels. You also cannot see product margin % without customization. And if you want a Cost field in your margin "report", get ready to spend a bunch of money for a developer to build out custom reports!